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IGF-I Analog

IGF-I Analog

This IGF-I peptide analog was able to inhibit the autophosphorylation of the IGF-I receptor by IGF-I as well as the growth of several different cell types, including prostate carcinoma cells and SV40-transformed cells. Such analogs might be useful in treating abnormal cell growth.

产品货号: KS031011

序列:CYAAPLKPAKSC-OH (trifluoroacetate salt) (Disulfide bond)

纯度:≥95%

分子式:C<sub>55</sub>H<sub>88</sub>N<sub>14</sub>O<sub>15</sub>S<sub>2</sub>

分子式: C55H88N14O15S2

分子量:1249.52

外观:冻干粉末

CAS#:147819-32-7

储存条件:Store at -20°C or -80°C

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This IGF-I peptide analog was able to inhibit the autophosphorylation of the IGF-I receptor by IGF-I as well as the growth of several different cell types, including prostate carcinoma cells and SV40-transformed cells. Such analogs might be useful in treating abnormal cell growth.

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参考文献:

Z.Pietrzkowski et al., Cancer Res., 52, 6447 (1992)
Z.Pietrzkowski et al., Cancer Res., 53, 1102 (1993)
G.Camarero et al., Dev. Biol., 262, 242 (2003)
L.Croci et al., Cell Death Differ., 18, 48 (2011)

参考文献:

  • 内容
    • 商品名称: IGF-I Analog
    • 产品货号: KS031011
    • 序列: CYAAPLKPAKSC-OH (trifluoroacetate salt) (Disulfide bond)
    • 纯度: ≥95%
    • 分子式: C<sub>55</sub>H<sub>88</sub>N<sub>14</sub>O<sub>15</sub>S<sub>2</sub>
    • 分子量: 1249.52
    • 外观: 冻干粉末
    • CAS#: 147819-32-7
    • 储存条件: Store at -20°C or -80°C

    This IGF-I peptide analog was able to inhibit the autophosphorylation of the IGF-I receptor by IGF-I as well as the growth of several different cell types, including prostate carcinoma cells and SV40-transformed cells. Such analogs might be useful in treating abnormal cell growth.

    参考文献:

    Z.Pietrzkowski et al., Cancer Res., 52, 6447 (1992)
    Z.Pietrzkowski et al., Cancer Res., 53, 1102 (1993)
    G.Camarero et al., Dev. Biol., 262, 242 (2003)
    L.Croci et al., Cell Death Differ., 18, 48 (2011)

关键词:

肽类药物,创新药物,肽类种子库

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