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β-Amyloid (1-42) (human)

β-Amyloid (1-42) (human)

42 残基肽被认为是阿尔茨海默病患者、老年人和 21 三体综合征(唐氏综合症)患者血管和斑块丝的主要亚基。无效控制。 序列: H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp- Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH 单字母序列: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

产品货号: KS011002

序列:DAEFRHDSGYEVHHQKLVFF AlaGluAspValGlySerAsnLysGlyAlaIleIleGlyLeuMetValGlyGlyValValIleAlaOH

纯度:≥95%

分子式:C<sub>203</sub>H<sub>311</sub>N<sub>55</sub>O<sub>60</sub>S<sub>1</sub>

分子式: C203H311N55O60S1

分子量:4514.04

外观:冻干粉末

CAS#:107761-42-2

储存条件:Store at -20 ± 5 °C

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42 残基肽被认为是阿尔茨海默病患者、老年人和 21 三体综合征(唐氏综合症)患者血管和斑块丝的主要亚基。无效控制。 序列: H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp- Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH 单字母序列: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

应用 :

参考文献:

REFERENCES:
J.Kang et al., Nature, 325, 733 (1987)
D.Goldgaber et al., Science, 235, 877 (1987)
J.Murrell et al., Science, 254, 97 (1991)
Neurobiology of Aging, 13, No.5 (1992)
G.Bitan et al., Proc. Natl. Acad. Sci. USA, 100, 330 (2003)
A.Jan et al., Nat. Protoc., 5, 1186 (2010)
W.B.Stine et al., Methods Mol. Biol. , 670, 13 (2011)

引文:
Walker, Douglas G., et al. Cells 8, no. 7 (2019): 766 »
Yen, Kelvin, et al. Scientific Reports 8.1 (2018): 14212 »
Hopping, Gene, et al. Elife 3 (2014): e01681 »
Scimemi, Annalisa, et al.Acta Pharmacologica Sinica 30.4 (2009): 388-395 »
Qin, Zhen-xia, et. al. Acta Pharmacologica Sinica 30.4 (2009): 388-395 »
Qin, Zhenxia, et al. Neuroscience Letters 444.3 (2008): 217-221 »

参考文献:

  • 内容
    • 商品名称: β-Amyloid (1-42) (human)
    • 产品货号: KS011002
    • 序列: DAEFRHDSGYEVHHQKLVFF AlaGluAspValGlySerAsnLysGlyAlaIleIleGlyLeuMetValGlyGlyValValIleAlaOH
    • 纯度: ≥95%
    • 分子式: C<sub>203</sub>H<sub>311</sub>N<sub>55</sub>O<sub>60</sub>S<sub>1</sub>
    • 分子量: 4514.04
    • 外观: 冻干粉末
    • CAS#: 107761-42-2
    • 储存条件: Store at -20 ± 5 °C

    42 残基肽被认为是阿尔茨海默病患者、老年人和 21 三体综合征(唐氏综合症)患者血管和斑块丝的主要亚基。无效控制。 序列: H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp- Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH 单字母序列: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

    参考文献:

    REFERENCES:
    J.Kang et al., Nature, 325, 733 (1987)
    D.Goldgaber et al., Science, 235, 877 (1987)
    J.Murrell et al., Science, 254, 97 (1991)
    Neurobiology of Aging, 13, No.5 (1992)
    G.Bitan et al., Proc. Natl. Acad. Sci. USA, 100, 330 (2003)
    A.Jan et al., Nat. Protoc., 5, 1186 (2010)
    W.B.Stine et al., Methods Mol. Biol. , 670, 13 (2011)

    引文:
    Walker, Douglas G., et al. Cells 8, no. 7 (2019): 766 »
    Yen, Kelvin, et al. Scientific Reports 8.1 (2018): 14212 »
    Hopping, Gene, et al. Elife 3 (2014): e01681 »
    Scimemi, Annalisa, et al.Acta Pharmacologica Sinica 30.4 (2009): 388-395 »
    Qin, Zhen-xia, et. al. Acta Pharmacologica Sinica 30.4 (2009): 388-395 »
    Qin, Zhenxia, et al. Neuroscience Letters 444.3 (2008): 217-221 »

关键词:

肽类药物,创新药物,肽类种子库

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